Are There Any Other Precautions Or Warnings For This Medication
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Diabetic ketoacidosis : Empagliflozin has been associated with DKA. This is a potentially life-threatening condition caused by not having enough insulin in the blood to use the glucose in the bloodstream. When this happens, the body starts to burn ketones for fuel and can make the blood acidic. This condition is more likely to develop if you are following a very low carbohydrate diet, are dehydrated, or have consumed a large amount of alcohol. Symptoms of DKA include:
- difficulty breathing
- unusual fatigue or sleepiness
If you experience these symptoms, get immediate medical help.
Cholesterol: Empagliflozin can cause increased levels of low-density lipoprotein , a type of cholesterol in the bloodstream. If you are at risk of developing high cholesterol or you have high cholesterol levels before starting empagliflozin, discuss with your doctor how this medication may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Your doctor will monitor your cholesterol levels regularly while you are taking this medication.
Can Taking Jardiance Cause Anxiety
But anxiety is a common condition among people who are dealing with long-term health conditions, such as type 2 diabetes and heart disease.
There are many ways to try to cope with anxiety, such as deep breathing exercises. But if these coping strategies arent enough, talk with your doctor. They can help you find the right treatment option for treating your anxiety.
Jardiance Contraindications & Warnings
Jardiance is not the right medication for everyone. Because it works by increasing the kidneys filtration of blood sugar, it is not appropriate for patients with severe or end-stage kidney disease or who are on dialysis. It should also not be given to anyone with a known hypersensitivity to empagliflozin, the active ingredient in Jardiance. In addition, people with diabetic ketoacidosis are not good candidates for Jardiance therapy. Jardiance is not for use in patients with Type 1 diabetes.
Jardiance comes with several warnings, including:
- The potential to cause low blood pressure in the elderly and in patients with renal impairment, low blood pressure, or who are taking diuretics
- The need to monitor patients for signs of
- Increase in bad cholesterol levels
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Alternatives For Type 2 Diabetes
Below are examples of other drugs that are used to treat type 2 diabetes. Some of these medications are in the same drug class as Jardiance, and some are in a different drug class. These different drug classes work in varying ways to lower blood sugar.
Sodium-glucose co-transporter 2 inhibitors
You may wonder how Jardiance compares to other medications that are prescribed to treat type 2 diabetes. Below are comparisons between Jardiance and several medications.
When Is Diabetes Medication Needed
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Synjardy And Synjardy Xr Can Cause Serious Side Effects Including:
Lactic acidosis . Metformin hydrochloride, one of the medicines in SYNJARDY and SYNJARDY XR, can cause lactic acidosis, a rare but serious condition that can cause death. Lactic acidosis is a medical emergency and must be treated in a hospital.
Stop taking SYNJARDY and SYNJARDY XR and call your healthcare provider right away or go to the nearest hospital emergency room if you get any of the following symptoms of lactic acidosis: feel very weak and tired have unusual muscle pain have trouble breathing have unexplained stomach or intestinal problems with nausea and vomiting, or diarrhea have unusual sleepiness or sleep longer than usual feel cold, especially in your arms and legs feel dizzy or lightheaded have a slow or irregular heartbeat.
You have a higher chance of getting lactic acidosis with SYNJARDY or SYNJARDY XR if you: have moderate to severe kidney problems have liver problems drink a lot of alcohol get dehydrated have certain x-ray tests with injectable dyes or contrast agents have surgery or other procedure for which you need to restrict the amount of food and liquid you eat and drink have congestive heart failure have a heart attack, severe infection, or stroke, or are 65 years of age or older.
Do not take SYNJARDY or SYNJARDY XR if you:
SYNJARDY or SYNJARDY XR may cause serious side effects, including:
Jardiance Side Effects And How To Avoid Them
Jardiance is a brand-name prescription drug that, along with diet and exercise, helps lower blood sugar in patients with Type 2 diabetes and reduce the risk of cardiovascular death in patients with both Type 2 diabetes and cardiovascular disease. Empagliflozin works by increasing the kidneys removal of glucose from the blood into the urine. Jardiance has several effects on the body and may not be right for everyone. Understanding the side effects, warnings, and drug interactions will help patients balance the pros and cons of taking Jardiance.
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How Should I Use This Medication
The usual starting dose of empagliflozin is 10 mg taken by mouth once a day. For people with type 2 diabetes, depending on how effectively it reduces your blood glucose, your doctor may increase the dose to 25 mg taken once a day.
Empagliflozin may be taken at any time of the day, with or without food. The tablet must be swallowed whole. Do not cut or chew the tablets.
Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is less than 12 hours until your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.
Do not dispose of medications in wastewater or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.
Natural Remedies For Lowering Diabetes
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Jardiance And Other Medications
Below is a list of medications that can interact with Jardiance. This list does not contain all drugs that may interact with Jardiance.
Before taking Jardiance, be sure to tell your doctor and pharmacist about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.
If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.
Jardiance and insulin and other diabetes drugs
Diabetes drugs are often taken together to lower blood sugar levels. However, taking Jardiance with certain diabetes drugs can increase your risk for hypoglycemia . These drugs include insulin and other medications that increase insulin levels in the body.
Examples of insulin medications include:
Talk with your doctor about the risk of hypoglycemia with each diabetes medication you take. Also talk about how the risk is increased if you take a combination of diabetes drugs. Your doctor may adjust the dosage of Jardiance or your other diabetes medications to reduce the risk of hypoglycemia.
Jardiance and certain blood pressure drugs
Taking Jardiance with certain blood pressure medications, such as diuretics , can increase the risk of low blood pressure. This is because diuretic drugs and Jardiance both increase urination. Urination moves fluid out of the body. This can lead to dehydration and low blood pressure.
Pay Attention To Blood Pressure
Jardiance has effects similar to a diuretic, so it can reduce blood volume and blood pressure. Be on the lookout for symptoms of low blood pressure such as dizziness when standing up, fainting, lightheadedness, drowsiness, blurred vision, nausea, and cold, clammy skin. If youre having problems with low blood pressure when taking Jardiance, it may help to purchase a blood pressure device and regularly monitor and record your blood pressure.
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Can Jardiance Cause Weight Loss
Jardiance use may cause a small amount of weight loss. People taking the drug in clinical trials reported losing a little weight compared with people who took a placebo . However, it isnt clear whether this is due to Jardiance or other factors, such as changes in diet and exercise.
If youre concerned about losing weight while taking Jardiance, talk with your doctor. They may recommend ways for you to help manage your weight. In some cases, your doctor may have you stop taking Jardiance and try a different medication for your condition.
How Long Do Jardiance Side Effects Last
Common side effects of Jardiance may resolve the longer the medicine is taken. Jardiance typically clears from the body within a few days , so any minor side effects such as increased urination should fade within a day or two after the drug is discontinued. However, infections, liver abnormalities, and kidney injury may take days or weeks to resolve.
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Tell Your Healthcare Provider About All Your Medical Conditions And Medications
Because of the risk of side effects, you should tell your healthcare provider about:
- Any physical conditions you may have, particularly heart, circulation, blood pressure, pancreas, kidney, or urinary tract problems
- All medications you are currently taking and
- All over-the-counter medications, supplements, and herbal remedies you take
Always talk to a doctor, pharmacist, or another healthcare professional, if you experience any side effects when taking Jardiance.
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Will I Still Lose Weight If I Take Jardiance With Metformin
Yes, you may achieve weight loss if you are taking metformin in combination with Jardiance. In a 24-week long clinical study with over 600 patients, Jardiance given as add-on therapy to metformin significantly improved weight loss. These patients were not adequately controlled on metformin alone.
Table 1. Weight changes for Jardiance when used with metformin
|Jardiance 10 mg + metformin|
Weight loss was also significant when Jardiance was used with metformin and a sulfonylurea in a study over 24-weeks long.
How Jardiance Works For Diabetes
Jardiance works by excreting blood sugars through the kidneys. Normally kidneys reabsorb all the blood sugars that go through them. Jardiance makes it easier to urinate excessive blood sugars through the kidneys. It is almost like mechanical unloading. You may realize that newly diagnosed or uncontrolled diabetic patients also urinate a lot. They urinate a lot because their blood sugars exceed the kidneys capacity to re-absorb the sugar . That is because their sugars run way too high. Jardiance, however, helps your kidneys to excrete blood sugars even when your blood sugars are only in the high 100 or low 200 range. So is peeing the blood sugar necessarily a good thing? Well, that depends.
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Can You Take Jardiance If You Dont Have Diabetes
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