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Lantus Basics And Classification
Lantus is classified as a long-acting insulin. It contains the active drug insulin glargine, which is a biologic drug. Biologic drugs are made from parts of living cells.
Lantus is available in a biosimilar form called insulin glargine-yfgn .
Lantus comes as a liquid solution thats given as an injection under your skin.
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What Are The Side Effects Of Lantus Injections
Common side effects include low blood sugar, redness and skin thickening at the injection site, and weight gain. Lantus is a prescription medication used to treat people with type 1 and type 2 diabetes for the control of high blood sugar. Lantus may be used along with fast-acting insulin or oral medications to control blood sugar.
How often do you need to take Lantus insulin?
Lantus is a long-acting insulin that should be injected below the skin once daily as directed by your doctor. On rare occasions, your physician may direct you to take Lantus two times daily. Take Lantus the same time every day. 2. Prepare your insulin. A rapid- or short-acting insulin is often prescribed with Lantus.
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Example #: Carbohydrate Coverage At A Meal
First, you have to calculate the carbohydrate coverage insulin dose using this formula:
CHO insulin dose = Total grams of CHO in the meal ÷ grams of CHO disposed by 1 unit of insulin .
For Example #1, assume:
- You are going to eat 60 grams of carbohydrate for lunch
- Your Insulin: CHO ratio is 1:10
To get the CHO insulin dose, plug the numbers into the formula:
CHO insulin dose =
- The carbohydrate coverage dose is 6 units of rapid acting insulin.
- The high blood sugar correction dose is 2 units of rapid acting insulin.
Now, add the two doses together to calculate your total meal dose.
Carbohydrate coverage dose + high sugar correction dose = 8 units total meal dose!
The total lunch insulin dose is 8 units of rapid acting insulin.
How Many Units Of Insulin Do I Need For 400 Blood Sugar
In a healthy individual, one unit of insulin should cause their blood sugar level to drop 30-50 mg/dL, However, the number of units of insulin needed for people with diabetes depends on factors such as:
- Type of insulin
- Site of injection
- Use of oral diabetes medications
- Comorbid conditions such as kidney failure, untreated hypothyroidism, or which temporarily increase insulin resistance
- Time since your last carb-rich meal
Theoretically, to reduce 400 mg/dL blood sugar to about 100 mg/dL, you would need at least 10 units of insulin. However, depending on your weight and other factors, a higher dose of insulin is almost always required.
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Lantus Dosage For Children
The FDA has approved Lantus in children as young as 6 years of age to treat Type 1 diabetes. Healthcare providers may, however, prescribe Lantus off-label to treat children and adolescents with Type 2 diabetes or newborns diagnosed with transient neonatal diabetes mellitus. As with adults, Lantus doses are ultimately based on fasting blood sugar levels. Each dose of Lantus is injected subcutaneously once daily at the same time every day.
Standard dosage for children ages 6 and older: Doses will vary recommended dose is 30% to 50% of the total daily insulin regimen
Maximum dosage for children ages 6 and older: Not specified
The High Blood Sugar Correction Factor:
Correction Factor = 1800 ÷Total Daily Insulin Dose = 1 unit of insulin will reduce the blood sugar so many mg/dl
This can be calculated using the Rule of 1800.
= 1800 ÷ TDI = 1 unit insulin will drop reduce the blood sugar level by 45 mg/dl
While the calculation is 1 unit will drop the blood sugar 45 mg/dl, to make it easier most people will round up or round down the number so the suggested correction factor may be 1 unit of rapid acting insulin will drop the blood sugar 40-50 mg/dl.
Please keep in mind, the estimated insulin regimen is an initial best guess and the dose may need to be modified to keep your blood sugar on target.
Also, there are many variations of insulin therapy. You will need to work out your specific insulin requirements and dose regimen with your medical provider and diabetes team.
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How Much Insulin Is Too Much To Take For High Blood Sugar
Ideally, you should be able to correct your blood sugar with an appropriate insulin dose. How much insulin is too much varies based on how sensitive your body is to insulin.
If you have higher-than-expected blood sugar , you should check your urine for ketones. The presence of ketones suggests your bodys cells are having trouble getting enough glucose. You could be at risk for a serious condition called diabetic ketoacidosis if you have ketones in your urine.
In this instance, you need extra help correcting your blood sugar. You should seek emergency medical attention instead of trying to keep injecting insulin to lower your blood sugar.
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Important Safety Information For Lantus 100 Units/ml
Lantus is contraindicated during episodes of hypoglycemia and in patients with hypersensitivity to insulin glargine or any of the excipients in LANTUS.
Warnings and PrecautionsInsulin pens, needles, or syringes must never be shared between patients. Do NOT reuse needles.
Monitor blood glucose in all patients treated with insulin. Modify insulin regimen only under medical supervision. Changes in insulin regimen including, strength, manufacturer, type, injection site or method of administration may result in the need for a change in insulin dose or an adjustment in concomitant drugs.
Repeated insulin injections into areas of lipodystrophy or localized cutaneous amyloidosis may result in hyperglycemia sudden change in the injection site has been reported to result in hypoglycemia. Advise patients to rotate injection site to unaffected areas and closely monitor for hypoglycemia.
Do not dilute or mix Lantus with any other insulin or solution. If mixed or diluted, the solution may become cloudy, and the onset of action/time to peak effect may be altered in an unpredictable manner. Do not administer Lantus via an insulin pump or intravenously because severe hypoglycemia can occur.
Hypoglycemia is the most common adverse reaction of insulin therapy, including Lantus, and may be life-threatening.
Severe life-threatening, generalized allergy, including anaphylaxis, can occur. Discontinue Lantus, treat and monitor until symptoms resolve.
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