What Is Emergency Glucagon
Most people have heard of the EpiPen it can save someones life if theyre having a severe allergic reaction to things like a bee sting or peanuts. Most people dont know about emergency glucagon.
Glucagon is a hormone produced by your pancreas that works by telling your liver to release glycogen , preventing low blood sugars in non-diabetic people.
Emergency glucagon is used to treat severe low blood sugar primarily in people with any type of diabetes who take insulin or other diabetes medications.
*Make sure you know where your classmate or student keeps their emergency glucagon.
While people with diabetes do produce glucagon, they cannot always produce the amount needed during severing low blood sugar events. And that is why emergency glucagon is so important.
What If The 15
If you dont feel better after three tries, or if your symptoms get worse, call your healthcare provider or 911. Healthcare providers can use a medication called glucagon. They inject it with a needle or squirt it up your nose. Glucagon is also available for home use. Your healthcare provider can prescribe it and teach a family member or friend how to use it in the event of severe hypoglycemia.
What Is Canine Low Blood Sugar
Sugar is your dogs main source of energy. If your dog is experiencing low blood sugar then their ability to properly function decreases and their energy levels will decrease, too. In extreme situations low blood sugar can cause serious health issues such as black out or even death.
When you think of low blood sugar you probably think of diabetes, but it is important to know that there are many other reasons that your dog may be experiencing low blood sugar, such as pregnancy, cancer, kidney failure, infection, or ingestion of something toxic. Keep in mind any other symptoms that your dog may be exhibiting along with the signs of low blood sugar so that your veterinarian has a better picture of what might be causing your dog to experience low blood sugar.
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Hypoglycemia And Low Blood Sugar
What are the symptoms of hypoglycemia? While each child may experience symptoms of hypoglycemia differently, the most common include: shakiness dizziness sweating hunger headache irritability pale skin color sudden moodiness or behavior changes, such as crying for no apparent reason clumsy or jerky movements difficulty paying attention or confusion What causes hypoglycemia? The vast majority of episodes of hypoglycemia in children and adolescents occur when a child with diabetes takes too much insulin, eats too little, or exercises strenuously or for a prolonged period of time. For young children who do not have diabetes, hypoglycemia may be caused by: Single episodes: Stomach flu, or another illness that may cause them to not eat enough fasting for a prolonged period of time prolonged strenuous exercise and lack of food Recurrent episodes: accelerated starvation, also known as ketotic hypoglycemia, a tendency for children without diabetes, or any other known cause of hypoglycemia, to experience repeated hypoglycemic episodes. medications your child may be taking a congenital error in metabolism or unusual disorder such as hypopituitarism or hyperinsulinism.Continue reading > >
A Low Blood Sugar Level Without Diabetes
A low blood sugar level is uncommon in people who do not have diabetes.
Possible causes include:
- a gastric bypass
- other medical conditions, such as problems with your hormone levels, pancreas, liver, kidneys, adrenal glands or heart
- some medicines, including quinine
See a GP if you think you keep getting symptoms of a low blood sugar level. They can arrange some simple tests to check if your blood sugar level is low and try to find out what’s causing it.
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Structural Analysis And Synthesis
Purified animal-sourced insulin was initially the only type of insulin available for experiments and diabetics. was the first to produce the crystallised form in 1926. Evidence of the protein nature was first given by , , and Philip A. Shaffer in 1924. It was fully proven when Hans Jensen and Earl A. Evans Jr. isolated the amino acids phenylalanine and proline in 1935.
The amino acid structure of insulin was first characterized in 1951 by , and the first synthetic insulin was produced simultaneously in the labs of at the and at in the mid-1960s. was achieved by Chinese researchers in 1965. The complete 3-dimensional structure of insulin was determined by in ‘s laboratory in 1969.
The first genetically engineered, synthetic “human” insulin was produced using in 1978 by and at the of the in collaboration with at . Genentech, founded by Swanson, Boyer and , went on in 1982 to sell the first commercially available biosynthetic human insulin under the brand name . The vast majority of insulin used worldwide is biosynthetic recombinant “human” insulin or its analogues. Recently, another approach has been used by a pioneering group of Canadian researchers, using an easily grown plant, for the production of much cheaper insulin.
Two other Nobel Prizes have been awarded for work on insulin. British molecular biologist , who determined the of insulin in 1955, was awarded the 1958 . received the 1977 Nobel Prize in Medicine for the development of the for insulin.
Possible Causes With Diabetes
Diabetes affects your bodys ability to use insulin. Think of insulin as the key that unlocks your cells, letting in glucose for energy.
If you have diabetes, a variety of treatments can help the cells in your body use the glucose in your blood. Among these are insulin injections and oral medications that increase insulin production.
If you take too much of these types of medications, your blood sugar may drop too low. You may also sometimes experience low blood sugar if you plan to eat a big meal but then do not eat enough.
Skipping meals, eating less than usual, or eating later than usual but taking your medication at your usual time can also lead to low blood sugar levels.
Unplanned excess physical activity without eating enough can also cause a drop in blood sugar levels.
Drinking alcohol when youre on these medications can also lead to low blood sugar, especially if it replaces food. When your body is trying to get rid of alcohol, it becomes worse at managing blood sugar levels.
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Low Blood Sugar Chart And Action Plan
Low blood sugar is also called hypoglycemia. The numbers below represent values in the hypoglycemic range and require action to bring blood sugar levels up into a normal range.
|Alert Level and Treatment Plan|
|50 mg/dL or under||Red Flag: Blood sugar is critically low and requires immediate treatment.|
If a person is unable to speak and/or is not alert, treat with glucagon via injection or nasal spray. Call emergency medical response if necessary. Do not place food or drink into the mouth.
If a person is alert and able to speak clearly, treat with 15 grams of rapid-acting carbohydrate such as glucose gel, 4 oz regular soda, or fruit juice. Re-test blood sugar in 15 minutes and repeat as needed to bring blood sugar within range.
|51-70 mg/dL||Red Flag: Blood sugar is below normal levels and requires immediate treatment.|
Treat with 15 grams of rapid-acting carbohydrate and re-test in 15 minutes. Repeat treatment as needed to bring blood sugar within range.
|71-90 mg/dL||Yellow Flag: Blood sugar levels should be watched and treated as needed.|
If youre having symptoms of low blood sugar, treat with 15 grams of rapid-acting carbohydrate and re-test in 15 minutes.
Repeat treatment or follow with a meal. If it is meal time, move forward with eating the meal. People often fall into this range when they are late for a meal or have been especially active.
What Causes Low Blood Glucose In People With Diabetes
Low blood glucose levels can be a side effect of insulin or some other medicines that help your pancreas release insulin into your blood. Taking these can lower your blood glucose level.
Two types of diabetes pills can cause low blood glucose
- sulfonylureas, usually taken once or twice per day, which increase insulin over several hours
- meglitinides, taken before meals to promote a short-term increase in insulin
The following may also lower your blood glucose level
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Nighttime Low Blood Sugar
While low blood sugar can happen at any time during the day, some people may experience low blood sugar while they sleep. Reasons this may happen include:
- Having an active day.
- Being physically active close to bedtime.
- Taking too much insulin.
- Drinking alcohol at night.
Eating regular meals and not skipping them can help you avoid nighttime low blood sugar. Eating when you drink alcohol can also help. If you think youre at risk for low blood sugar overnight, have a snack before bed.
You may wake up when you have low blood sugar, but you shouldnt rely on that. A continuous glucose monitor can alert you with an alarm if your blood sugar gets low while youre sleeping.
What Happens To An Older Cat With Diabetes
Diabetes in Older Cats. Without insulin, the body cant utilize glucose. In diabetic cats, excess glucose is eliminated by the kidneys, producing frequent urination. There is a need to compensate for the increased urination by drinking unusual amounts of water. Pancreatitis, hyperthyroidism, medications such as megestrol acetate ,
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How To Prevent Nocturnal Hypoglycemia
Start by talking to your doctor about a bedtime blood sugar target. Ask about your risk for hypoglycemia and if you should get a glucagon kit. Dont miss dinner, exercise before bedtime, or drink alcohol at night. Have a sugar and protein snack before bedtime, like a wheat cracker with cheese.
If you have had symptoms of nocturnal hypoglycemia, work with your doctor on a prevention plan. This may include switching to a longer acting insulin that does not peak during sleep, or changing your insulin dose. You might be asked to set an alarm and check your blood sugar in the early morning for a while. For people at high risk for nocturnal hypoglycemia, a continuous glucose monitor may be the best solution. A CGM can check your blood sugar every 5 minutes and can set off an alarm if your sugar gets too high or too low.
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Why Am I Having Lows
If you are experiencing low blood sugar and youre not sure why, bring a record of blood sugar, insulin, exercise and food data to a health care provider. Together, you can review all your data to figure out the cause of the lows.
The more information you can give your health care provider, the better they can work with you to understand what’s causing the lows. Your provider may be able to help prevent low blood sugar by adjusting the timing of insulin dosing, exercise and meals or snacks. Changing insulin doses or the types of food you eat may also do the trick.
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Insulin Chart For Blood Sugar
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Using Emergency Glucagon On A Person Experiencing Severe Low Blood Sugar
- Make sure they are physically safe if unconscious or seizing. If a person starts to experience a seizure, for example, when they are standing up or walking , its important to carefully move their body to a safe position and location. Another example may be if they are sitting at the kitchen table, on a treadmill, etc. Before or while they experience a seizure, do your best to make sure they are physically safe from other danger, falling, or even nearby cars if the seizure occurs on the side of the road.
- Locate their emergency glucagon. The most important thing a person with diabetes can do is teach their friends, family, and coworkers about the location of their emergency glucagon. By the nightstand, in their office desk, in a fanny pack they wear while exercising wherever it might be, its important to ask and know the location of their emergency glucagon treatment.
- Follow the directions on new glucagon treatment options:
- Nasal glucagon: Remove the cap. Insert the tip gently into the persons nostril and press the plunger end firmly until the green line disappears.
- Auto-inject pen: Remove the red or grey cap. Press the yellow end of the pen against the persons upper arm, stomach, or thigh and hold for 5 seconds or 10 seconds .
- Pre filled syringe: Remove the cap of the syringe. Pinch the skin and insert the needle at a 90degree angle. Push the plunger down as far as it will go. Inject the glucagon into the persons upper arm, stomach, or thigh.
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Check Your Blood Sugar Level Regularly
The best way to become familiar with your blood sugar trends is to check your blood glucose. Checking your blood glucose regularly will help you identify how you respond when your blood sugar is high or low.
People who check their blood sugar regularly tend to have better blood glucose control compared to those who dont.
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Normal Blood Sugar Level
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Hypoglycemia Tests And Diagnosis
To diagnose nondiabetic hypoglycemia, your doctor will do a physical exam and ask questions about any medicines you take. Theyâll want to know all about your health and any history of diseases or stomach surgery.
Theyâll check your blood glucose level, especially when you are having symptoms. Theyâll also check to see if you feel better when your sugar goes back to a normal level.
If your doctor suspects hypoglycemia, you may have to fast until you start to have symptoms. Theyâll test your blood glucose level at different times throughout the fast.
To check for reactive hypoglycemia, you may have to take a test called a mixed-meal tolerance test . For this, you take a special drink that raises your blood glucose. The doctor will check your blood glucose levels over the next few hours.
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Your Diabetes Devices And Hypoglycemia
Several insulin pumps are now available that make managing blood sugar levels easier, particularly when connected to a glucose meter or a CGM.
Some of the most important advantages of CGM devices are the improved insulin control and the ability to detect trends and lows early. With improved technology, it is now possible for parents to track blood sugar trends in their kids even when they are hundreds of miles apart .
In addition, automated insulin delivery systems, also known an artificial pancreas or a hybrid closed-loop system, will automatically adjust insulin to match your bodys need to help you spend more time in your target range.
Resources that provide people with T1D and their families with more detailed information about pumps and CGM devices are available through JDRF here. For people looking for a deeper understanding of technology that helps people with T1D better manage their blood sugar, JDRF resources are available here.