Jardiance Contraindications & Warnings
Jardiance is not the right medication for everyone. Because it works by increasing the kidneys filtration of blood sugar, it is not appropriate for patients with severe or end-stage kidney disease or who are on dialysis. It should also not be given to anyone with a known hypersensitivity to empagliflozin, the active ingredient in Jardiance. In addition, people with diabetic ketoacidosis are not good candidates for Jardiance therapy. Jardiance is not for use in patients with Type 1 diabetes.
Jardiance comes with several warnings, including:
- The potential to cause low blood pressure in the elderly and in patients with renal impairment, low blood pressure, or who are taking diuretics
- The need to monitor patients for signs of
- Increase in bad cholesterol levels
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Who Is Jardiance Suitable For
Jardiance is recommended by the National Institute of Clinical Excellence as a treatment for type 2 diabetes under the following conditions:
- When diet and exercise do not provide adequate glycemic control
- When metformin is not appropriate due to patient intolerance
Jardiance is also recommended alongside metformin if a patient is at significant risk of hypoglycemia or cannot take a sulfonylurea. It can also be taken with either metformin or a sulfonylurea.
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Financial And Insurance Assistance
If you need financial support to pay for Jardiance, or if you need help understanding your insurance coverage, help is available.
Boehringer Ingelheim and Lilly, the manufacturers of Jardiance, offer a program called Jardiance Savings. For more information and to find out if youre eligible for support, visit the program website.
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How To Use Jardiance
Read the Medication Guide provided by your pharmacist before you start taking empagliflozin and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.
Tell your doctor if your condition does not improve or if it worsens.
Do Not Use Jardiance If:
There are several situations where this medication may not be the right choice for you. According to the FDA, the following should not use Jardiance:
- People with type 1 diabetes
- People with allergies or sensitivities to ingredients in Jardiance
- People with severe or end-stage kidney disease, including people who are on dialysis
- People with diabetic ketoacidosis
Please note that this list may not be complete, and there may be other situations where the use of this drug is not advisable.
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Overdose: What Happens If I Take Too Much Jardiance
There is limited research on the risk of Jardiance overdose or at what dose Jardiance can become toxic.
A 2020 case report detailed an incident in which a healthy woman overdosed on SGLT-2 inhibitors. Although there was moderate kidney impairment, the only notable side effect was frequent urination. After 36 hours, kidney function returned to normal, and there was no evidence of severe hypoglycemia.
This should not suggest that the risk of Jardiance overdose is lowparticularly in older adults, children, people with kidney disease or heart failure, or those taking certain medications.
Always keep medications out of the reach of children to avoid accidental overdose.
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What Are The Side Effects Of Jardiance
The side effects of Jardiance include:
- Problems with urination either a frequent urge to urinate, or little to no urinating
- Increased likelihood of urinary tract infections
- Signs of a genital infection such as pain, itching or a rash
- Hypoglycemia if taken with a medication that reduces blood glucose levels
- Increased cholesterol
- Feeling tired or light-headed
Please note the list above is not exhaustive. You should refer to the patient information leaflet in the medication for a full list of side effects.
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How Can I Stay Healthy While Taking Jardiance
Medications alone cannot treat type 2 diabetes. Although Jardiance is highly effective, it is meant to be used alongside diet and exercise as part of a holistic treatment plan.
Diets rich in whole grains, fruits, vegetables, legumes, and nuts can improve glycemic control in people with type 2 diabetes. You should reduce intake of refined grains, red/processed meats, and sugar-sweetened foods or drinks. Moderate alcohol consumption is also advised.
According to the American Diabetes Society, people with type 2 diabetes should undertake no less than 150 minutes of moderate to vigorous aerobic exercise per week. In addition to aerobic activities, you should aim to devote two to three days per week to moderate to vigorous resistance training.
Adherence to your treatment plan is key to maintaining optimal glycemic control. Missing doses or failing to follow your diet and exercise plan can take back the gains afforded by drugs like Jardiance. Consistency is key.
If you have trouble following your treatment plan, speak with your healthcare provider. By working together, youll be better able to find the solution best suited for you as an individual.
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How Insulin Affects Blood Sugar
Normally, the body releases a hormone called insulin when you eat food. Insulin helps move glucose from the bloodstream into your bodys cells. Your cells turn the sugar into energy.
People who have type 2 diabetes are usually resistant to insulin. This means that their body doesnt respond to insulin the way it should. Over time, people with type 2 diabetes may also stop making insulin.
Without the help of insulin, your bodys cells cant absorb glucose. This can affect how well the cells work in your body. Your blood levels of glucose can also become too high. High blood glucose levels are called hyperglycemia.
High blood glucose levels can cause many health problems. Areas of the body that can be affected include:
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What To Ask Your Doctor
Jardiance can be an effective treatment for improving blood sugar levels in people with type 2 diabetes . Jardiance is also effective for reducing the risk of cardiovascular death in people who have both type 2 diabetes and heart disease.
But this drug may cause side effects in some people. Its important to talk with your doctor to determine if the potential benefits of Jardiance treatment outweigh your risk for side effects.
Here are some example questions to get a conversation started with your doctor:
- Do my other medications raise my risk for side effects from Jardiance?
- With my current health and medical history, am I at higher risk for serious side effects from this drug?
- Do I need to stop taking Jardiance before my upcoming surgery?
- Is there anything I can do to prevent infections during my Jardiance treatment?
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